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Tissue Repair · compound evidence summary

BPC-157

An evidence summary of published preclinical research on BPC-157. This page is educational and summarizes findings reported in third-party scientific literature. No claims are made regarding safety or efficacy in humans.

Molecular Data

Formula
C62H98N16O22
Molecular weight
1419.5 g/mol
Sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV)

Compound Overview

BPC-157 is a synthetic pentadecapeptide composed of 15 amino acids and based on a sequence associated with a gastric protective protein. It has been investigated in rodent models of tendon, muscle, and gastrointestinal tissue response. Its reported stability in gastric fluid is one reason researchers have examined it, but animal observations have not established effects in humans.

Reported Mechanism (Preclinical)

Preclinical studies have examined growth-factor expression, nitric-oxide signaling, angiogenesis, and tissue remodeling in response to BPC-157. Some animal models report changes in granulation tissue and collagen deposition. These pathways are still being characterized; the publications below do not test this catalog lot or establish a clinical effect.

Mechanisms described here come from preclinical or in vitro research. They do not establish safety or efficacy for human use.

Key Research Highlights

  • Research question: Preclinical studies have examined growth-factor expression, nitric-oxide signaling, angiogenesis, and tissue remodeling in response to BPC-157.
  • Evidence boundary: publications do not establish the composition, safety, or efficacy of this catalog lot.

Published References

  1. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing.Gwyer et al. · Cell Tissue Res · 2019
  2. Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing.Brcic et al. · J Physiol Pharmacol · 2009
  3. Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia). Full and distended stomach, and vascular response.Sikiric et al. · Inflammopharmacology · 2006

These publications discuss the named compound or related research. They are not lot-specific tests of this catalog product.

Available for Research

Lab-tested compounds with lot-specific documentation where available.

View Product · BPC-157 View COA Library
FOR LABORATORY AND RESEARCH USE ONLY — NOT FOR HUMAN OR VETERINARY USE. This summary is educational and does not provide medical advice or establish clinical efficacy.